Unlock Your Physique’s Therapeutic Potential: The Sport-Altering X-Cells

July 16, 2024

Power ache that simply will not go away… regenerative therapies that value hundreds of {dollars}, but solely supply non permanent aid… previous accidents that progressively worsen over time…

Should you’re uninterested in this limitless cycle of frustration and disappointment, you are not alone. However what if there was a strategy to break away from this sample and unlock your physique’s true therapeutic potential?

Whereas it’d sound like science fiction, there is a new, cutting-edge revolutionary remedy that may supercharge your physique’s therapeutic talents by regenerating broken tissues, doubtlessly reversing years of wear and tear and tear and turbo-boosting your longevity within the course of.

Whether or not you are battling joint ache that is protecting you out of your favourite actions, fighting a neurological situation that is affecting your high quality of life, or just wanting to show again the clock on getting older, X cells could possibly be the game-changing resolution you have been looking for.

On this visitor submit, written by famend well being and longevity skilled Dr. John Lieurance, you may uncover how this breakthrough remedy is outperforming conventional stem cell therapies, providing hope for circumstances starting from arthritis to Alzheimer’s.

Dr. John Lieurance is a naturopathic doctor and chiropractic neurologist who has devoted over twenty years to pioneering breakthroughs within the fields of regenerative medication and pure well being. Because the founding father of Superior Rejuvenation and the developer of a number of proprietary therapies, Dr. Lieurance has a profound understanding of methods to harness the physique’s innate therapeutic powers to optimize well being and reverse continual circumstances. He’s additionally an excellent good friend of mine and a multi-time visitor on my podcast (yow will discover the podcast episodes he is been featured on right here, right here, right here, and right here).

With in depth expertise in therapies like stem cell therapy, PRP remedy, and ozone remedy, Dr. Lieurance is a real innovator on the forefront of integrative medication. His mission is to empower people with cutting-edge information and coverings that facilitate profound well being transformations.

Heads up: Dr. Lieurance shall be diving deep into among the most superior and potent methods in pure therapeutic, lots of which outpace typical medical approaches. You will need to take in each little bit of knowledge he shares on this article, so if you cannot get by it unexpectedly, it can save you it and return to it later — that is invaluable information you may need to revisit!

Bear in mind, you do not have to accept band-aid options or resign your self to a way forward for declining well being. Learn on to learn the way X cells could possibly be the important thing to unlocking your physique’s innate therapeutic potential and reclaiming the colourful, pain-free life you deserve.

Key “X Cell” Takeaways You will Uncover in This Article

• X cells, derived from adipose tissue of younger, wholesome donors, characterize a big development in stem cell remedy, outperforming conventional perinatal stem cells in varied features.
• X cells have superior survival charges (3–10 weeks) in comparison with perinatal stem cells (1–2 hours), permitting for longer-lasting regenerative results.
• The “complete meals” method of X cells, containing a various array of stem cell varieties and supporting components, gives a synergistic therapeutic impact just like the entourage impact seen in hashish therapeutics. 
• X cells present promise in treating a variety of circumstances, together with orthopedic points, neurological issues, autoimmune ailments, and age-related decline.
• “Stem-hacking” strategies (which you’ll be able to uncover extra about right here), such because the Purple, Blue, O2 protocol (combining purple gentle remedy, methylene blue, and hyperbaric oxygen), can improve the effectiveness of stem cell therapies. 
• Focused vitamins like melatonin (you may click on right here to hitch Dr. Lieurance’s MitoZen Membership, the place you may get the identical excessive dose of melatonin that I exploit), CoQ10, and fucoidan can help stem cell survival and performance, doubtlessly bettering the general success of stem cell remedy.

X Cells: The “Rolls Royce” of Stem Cells (by Dr. John Lieurance)

After working within the discipline of regenerative medication for over 25 years, I’ve seen many stem cell functions and quite a few kinds of stem cells. All of them have their distinctive traits, they usually all have their drawbacks. However I’ve lastly discovered a sort that adjustments the sport and surpasses all the remaining. 

Stem cells could be autologous (from your personal physique) or allogeneic (from a supply exterior your physique). The most typical autologous stem cells are from bone marrow or adipose tissue (extra generally generally known as physique fats). As a result of utilizing autologous stem cells is extra concerned and extra invasive, nearly all of clinics use allogeneic sources from perinatal tissue or exosomes (tiny vesicles secreted from stem cells that activate a rejuvenating impact) derived from these perinatal tissues. 

Initially, my clinic, Superior Rejuvenation, used stem cells and exosomes from perinatal sources for years with respectable outcomes. Till lately, I thought of them to be the most suitable choice for an off-the-shelf allogeneic stem cell. A couple of 12 months in the past, nevertheless, a brand new choice grew to become out there that I’ve discovered to be far more highly effective. 

Introducing X Cells: The Epitome of Regenerative Potential

X cells, named for his or her “further” power and viability, are derived from adipose tissue donated by younger, wholesome people, representing a paradigm shift in regenerative medication.

Comprising roughly 10 various kinds of stem cells, X cells supply a multifaceted method to tissue restore and regeneration.

One of many major constituents of X cells are adipose-derived stem cells (ADSCs) — or stem cells from fats — which have emerged as promising candidates for treating orthopedic, neurologic, and autoimmune circumstances. 

Amongst a myriad of different functions, X cells even have an enhanced capability to supply each endothelial cells and regenerate nerves, which makes them a superb alternative for treating hair loss, pores and skin rejuvenation, and sexual rejuvenation, leading to higher orgasms for ladies and an finish to erectile dysfunction in males. 

After cautious examination of the analysis you may discover cited all through this text, I strongly imagine X cells is likely to be the most suitable choice for anybody on the lookout for regeneration in orthopedic, neurologic, and autoimmune circumstances. 

The prevalence of X cells stems from a number of distinctive traits:

• Robust survival: X cells are resilient and may survive in harsh environments, equivalent to inside broken tissues the place we want them most. They will reside from 3–10 weeks, whereas most perinatal stem cell varieties solely survive 1–2 hours (if in any respect!).
• Quick-acting: X cells differentiate 4 occasions sooner than perinatal mesenchymal stem cells. This implies they’ll begin working sooner to regenerate your physique.
• Vascularization: X cells are superior at producing endothelial cells at a way more fast price. Which means extra blood provide to the brand new cells and tissues so the physique can herald all the required oxygen and vitamins to create cartilage, nerve tissue, ligaments, and muscle tissues.
• Inhibit most cancers formation: Muse cells contained in X cells inhibit most cancers and teratoma formation, making them far superior to different choices.
• Immune tolerance: X cells have the potential to ascertain immune tolerance.

A Various Array of Regenerative Cells in X Cells 

The wealthy reservoir of regenerative vitamins current in adipose tissue underscores its significance in regenerative medication. Analogous to complete meals that provide superior dietary worth in comparison with artificial counterparts, adipose tissue harbors a various array of stem cells important for tissue restore and regeneration.

The idea of the “entourage impact,” well known within the context of hashish therapeutics, elucidates the synergistic interactions amongst varied elements to produce enhanced therapeutic outcomes. 

Equally, adipose tissue serves as a reservoir of regenerative “complete meals” sources, comprising fibroblasts, ADSCs, Muse stem cells, endothelial progenitor cells, and supporting development components, collectively orchestrating a symphony of therapeutic processes. That’s why I name our bone marrow and adipose tissue the “complete meals” of regenerative medication.

Our clinic began utilizing each fats and bone marrow in stem cell therapies in 2005, and I haven’t discovered something that creates a regenerative final result as highly effective and sturdy. I’ve seen instances a decade or extra post-treatment and sufferers are nonetheless pain-free and residing their finest life.

X cells are a fancy combine containing a whole lot of stem cell varieties, development components, and supporting cells, together with:

• Mesenchymal stem cells (MSCs): MSCs are multipotent stromal cells that may differentiate into a wide range of cell varieties, together with bone cells (osteoblasts), cartilage cells (chondrocytes), fats cells (adipocytes), and others. They’re present in varied tissues, together with bone marrow, adipose tissue, and umbilical wire tissue. MSCs play a vital position in tissue restore, irritation regulation, and immune modulation, making them beneficial in regenerative medication and therapeutic functions. They usually make up 6–12% of X cells.  
• Hematopoietic stem cells: These are immature cells that may grow to be all kinds of blood cells, which in flip enable stem cells to engraft higher, enhancing survivability.
• Endothelial progenitor cells (EPCs): EPCs create endothelial cells which help the creation of latest blood vessels. This enables the cells to get vitamins that help survivability.
• Supporting stem cells: These embrace fibroblasts, endothelial cells, pericytes, and immune cells. They play a vital position within the total operate of X cells by offering structural help, secreting development components, and modulating the immune response. 
• Muse cells: Muse cells are a stress-tolerant inhabitants of stem cells present in each bone marrow and adipose tissue. They’re pluripotent, which means they’ll shapeshift into any cell line. They will additionally endure hostile environments, helping their survival in broken or injured tissues. They help tissues concerned within the mind and neurological features of our well being in addition to tissues associated to the lungs, thyroid, and pancreas. Moreover, Muse cells have inherent immunomodulatory properties that help calming down irritation and autoimmune circumstances, along with contributing to tissue regeneration and restore.
• Preadipocytes: Preadipocytes are probably the most ample cell kind within the collective of cells within the adipose tissue. Current proof means that this cell shares lots of the identical phenotypic markers and traits of MSCs, implicating its involvement in regeneration.

There are actually a whole lot of firms producing varied culture-expanded stem cells that are grown in a lab to make duplicates of a selected cell. They’re usually from placental origin or perinatal tissue.

My perspective is that it’s like white bread, devoid of the gamut of supporting and synergistic cell strains that present therapeutic. They lack the majesty in our bone and fats put there by creation itself. 

Some firms utilizing these “white bread” stem cells have began utilizing gene remedy to activate cells to turn into sure cell varieties. It actually sounds attractive and instructions the next worth level. However is this type of gene manipulation actually mandatory when nature has already supplied our our bodies with all the things they should heal and regenerate? 

Unraveling the Mysteries of Stem Cell Isolation

Adipose-derived stem cells are usually remoted from the stromal vascular fraction (SVF), or assortment of cells throughout the adipose tissue. The SVF is taken into account the “complete meals” of adipose tissue. Analysis evaluating the isolation of ADSCs versus combining them with the SVF has concluded that SVF therapy confirmed superior, statistically vital outcomes in comparison with ADSC therapy alone.

One other examine discovered a bonus of SVF over ADSCs in two elementary areas. First, the variety of cells could also be responsible for the higher therapeutic outcomes noticed, not in contrast to the entourage impact talked about earlier. Second, SVF is obtained with minimal contact with reagents, making it comparatively safer.

In contrast to typical isolation strategies that contain chemical processing, X cells are meticulously processed utilizing gravity alone, preserving their innate regenerative properties.

Clearly, with bone marrow and adipose, nature has packaged the correct assortment of regenerative properties completely, and X cells now appear to be an ideal instance of that.

Evaluating X Cells to Perinatal Stem Cells 

Higher Survival 

There’s an abundance of literature that helps the vastly superior survival price and regenerative potential of X cells in comparison with perinatal stem cells. 

In a nutshell, X cells survive longer, in order that they work longer and proceed the regeneration course of for weeks after implantation. Different stem cell sources, against this, die rapidly.  

Perinatal tissues have such poor survival, they might solely final 1 hour. Research have proven that allogeneic stem cells from perinatal tissues face challenges in long-term survival and immunogenicity after transplantation, impacting their therapeutic efficacy. That’s an enormous distinction in comparison with the three weeks that X cells can survive. In a single examine, X cells have been nonetheless current and alive 10 weeks later!

Perinatal stem cells have additionally been proven to be delicate to harsh environments as soon as transplanted. Analysis has proven that engraftment — the power of those stem cells to truly work — is weak with perinatal stem cells.

Superior Area of interest Formation 

As soon as stem cells are transplanted right into a joint or one other space of the physique, they face three attainable outcomes: they are going to survive and thrive, they are going to die, or they are going to turn into senescent (a everlasting state of sleep).

The area of interest, or the atmosphere the cells shall be subjected to, is a big think about figuring out the course these cells will take. A distinct segment could be both harsh or hospitable. Perinatal stem cells lack area of interest help as soon as launched into the physique, whereas the stem cell strains contained in X cells are sturdy and resist changing into burdened even when positioned right into a harsh atmosphere. 

Many continual accidents that stem cell remedy treats require these cells to endure difficult environments. What makes the atmosphere harsh is the extent of irritation, which can be related to oxidation. Analysis has proven that X cells have a excessive probability of survival in high-oxidation environments. They’re merely higher than every other stem cell strains studied. 

Not solely are X cells resilient to harsh environments, however they really have the power to quickly create a extra hospitable atmosphere as soon as they’re positioned there. They obtain this by bringing in endothelial cells that create a brand new blood provide, which then brings in vitamins like amino acids and oxygen. X cells additionally produce substances known as development components that additional help the growth and differentiation course of. The concept is that the gathering of this “complete meals” mixture of cells permits for fast growth of blood provide to start offering vitamins to the stem cells and new tissues they’re creating.

Immune Rejection 

Perinatal stem cells have a excessive immunological rejection price, which basically means your immune system kills them. This is the reason they trigger extra ache and irritation than X cells. 

Equally, all “cross-sex” umbilical stem cells (these that are positioned within the physique of somebody with a unique intercourse than the stem cells originated), have points with engraftment. In these instances, engraftment — the method of the stem cells really being assimilated into the therapy space — is doubtful, if it occurs in any respect. 

So as to forestall graft failure, the perinatal tissue would must be processed in order that the MSCs could be remoted and expanded, producing just one era in a bioreactor. Most firms do a number of generations of growth for increased yields, however this shortens the telomeres, and thus the cells’ viability and efficiency decline with every era.

Exosomes 

Stem cells not solely migrate to broken tissue and differentiate into varied cell strains to switch the broken cells, however additionally they connect in areas adjoining to broken cells and launch tiny vesicles known as exosomes. 

Exosomes are tiny packages of RNA. RNA carries info, and these little vesicles carry info from the stem cell. This encourages the broken cells in addition to wholesome cells within the space to enter a regenerative section and start to rebuild broken tissue with new, contemporary cells and tissue. Finally, it’s your personal cells and tissue that do the restore after the RNA within the exosomes showers the injured or weakened websites within the physique. 

Exosomes launched by stem cells present the first affect for regeneration. Whereas exosome manufacturing is troublesome to measure as a consequence of their extraordinarily small dimension and the truth that their yield depends upon a wide range of components, a scientist on this discipline whom I spoke with recommended that each perinatal and ADSC stem cells might produce a mean of 17 million exosomes per hour. Which means a typical perinatal stem cell produces solely 2.5% of what an X cell might create over 3 weeks.

That is 4,000% extra regenerative capability!

X Cells Clinically 

Mesenchymal stem cells have been profitable in varied therapies, together with Crohn’s illness and osteoarthritis of the knee. There have been over 200 medical stem cell trials using X cells, greater than every other stem cell supply so far. 

X cells are pure, not expanded, and processed with out dimethylsulfoxide (DMSO) or enzymes. Superior Rejuvenation is the primary clinic to make use of X cells for inside ear regeneration, and we plan to start medical trials quickly primarily based on constructive outcomes.

X Cells for the Mind and Nerves 

Analysis has proven that the neuroregenerative potential of X cells holds immense promise for treating circumstances equivalent to a number of sclerosis and neuropathy in addition to selling grownup neurogenesis within the brains of Alzheimer’s sufferers.

X cells are additionally exquisitely delicate to their atmosphere, receiving chemical signaling to turn into varied kinds of nerve cells. Analysis has proven that X cells carry additional vital benefits, as they’ve a bias to turn into mind and nerve tissues.

Stem-Hacking: Biohacking Stem Cell Remedy 

Most circumstances that may be handled utilizing stem cell remedy can be supported with the synergy of the Purple, Blue, O2 protocol pioneered by my clinic, Superior Rejuvenation. Very like the entourage impact with hashish, this protocol combines modalities that may synergistically help therapeutic.

Listed below are some focused stacks I exploit in my clinic to help stem cell remedy:  

• The Purple, Blue, O2 protocol: This can be a synergistic therapy combining purple gentle remedy, methylene blue, and hyperbaric oxygen remedy (HBOT). This professionaltocol additionally contains different photodynamic substances and cranial remedy through endonasal balloon manipulations, which intention to extend oxygen throughout the mind by bettering nasal respiration (for extra info, you may take a look at this podcast). 
• Purple gentle: A number of research have proven laser gentle remedy throughout the purple and near-infrapurple spectrums to help regenerative medication and cell remedy. This photobiomodulation will increase X cell survival and gene expression to scale back oxidative stress.
• Methylene blue: Methylene blue could improve the survival of cells important for central nervous system operate and fight degenerative neurological illness. Methylene blue was additionally present in an Alzheimer’s examine to modulate the migratory capability of grownup neural stem cells, bettering cell mobility. You possibly can click on right here to hitch Dr. Lieurance’s Mitozen Membership for entry to the perfect methylene blue merchandise!
• HBOT: Research on hyperbaric oxygen present that it will increase stem cell proliferation, the formation of latest blood cells, and healing.

For extra on the Purple, Blue, O2 protocol, you may snag a duplicate of Methylene Blue: Magic Bullet on Amazon (and take a look at our current podcast collectively to find extra about this matter). You may as well join an occasion with the three pioneers of the Purple, Blue, O2 protocol — Dr. Jason Sonners, Brian Richards of Sauna House, and myself, on Aug. 23, 2024, in particular person in Sarasota in addition to through livestream. You possibly can use low cost code BEN10 to avoid wasting 10% on tickets!

Stem-Hacking Focused Vitamins to Help Stem Cell Remedy

Most accidents and dysfunctional organs which might be handled utilizing stem cell remedy have excessive ranges of irritation, oxidative stress, and poor circulation. These so-called area of interest stressors restrict the survivability, differentiation, and total success of stem cell remedy.

Melatonin has been proven to guard stem cells towards oxidative stress in addition to calm irritation, thereby bettering stem cell survival. One examine went as far as to conclude that combining melatonin with stem cell remedy was superior to stem cell remedy alone.

Ben and I’ve recorded just a few podcast episodes discussing melatonin, significantly increased doses delivered rectally (as a consequence of its poor oral absorption). MitoZen’s Sandman line of high-dose melatonin additionally accommodates glutathione, which has additionally been proven to help ADSC survival.

Coenzyme Q10 (CoQ10) has been proven to guard stem cell getting older, and the mechanisms of cell senescence inhibited by CoQ10 have been demonstrated in analysis.

Fucoidan, present in brown algae and seaweed, is taken into account anti-senescent, anti-apoptotic, anti-tumor, anti-inflammatory, and anti-oxidative. Fucoidan enhances the bioavailability of endothelial progenitor cells, improves survival in mesenchymal stem cells, will increase proliferation, and amps up mobile practical properties.

At MitoZen.membership, we mix CoQ10 and fucoidan to make StemZen, a product particularly designed to stop senescence and maximize stem cells.

Methylene blue reduces area of interest stressors and helps the mitochondria in stem cells. MitoZen’s Lumetol Blue could be taken day by day to help and improve stem cell remedy. Take a look at the podcast episode Ben and I did on methylene blue right here.

Prolonged fasting additionally releases stem cells within the refeeding section. Utilizing these protocols and ideas can help the survival of those newly launched stem cells. MitoZen.membership has a Quick-Observe Quick Package which makes use of some of our most useful merchandise — Lumetol Blue, the StemZen bullet, and high-dose melatonin within the type of the Tremendous Sandman Bullet. Observe this hyperlink to find extra concerning the Quick-Observe Quick from MitoZen.membership.

Enhancing the survival price of implanted stem cells in unfavorable environments utilizing vitamins like melatonin and methylene blue, together with therapies equivalent to these within the Purple, Blue, O2 protocol, could be key to bettering the success of stem cell remedy.

Abstract

So, there you’ve gotten it! As you have explored on this article, X cells characterize a groundbreaking leap ahead in regenerative medication, providing hope for these fighting continual ache, degenerative circumstances, and age-related decline.

In contrast to conventional stem cell therapies, X cells harness the total energy of adipose tissue’s various mobile ecosystem, offering a “complete meals” method to therapeutic that far surpasses the capabilities of remoted or culture-expanded cells.

The outstanding survival charges of X cells — lasting weeks as a substitute of hours — mixed with their capability to thrive in harsh environments, make them an absolute game-changer within the discipline. From orthopedic accidents to neurological issues, and from autoimmune circumstances to sexual well being, X cells are opening new avenues for therapy that have been beforehand unimaginable.

However the potential of X cells would not cease there. By combining this cutting-edge remedy with “stem-hacking” strategies just like the Purple, Blue, O2 protocol and focused dietary help, you may additional amplify your physique’s innate therapeutic talents. This synergistic method not solely enhances the effectiveness of stem cell therapies but in addition promotes total mobile well being and longevity.

If you’re a affected person desirous about discovering out if X cells may enable you to with a well being situation, otherwise you’re a healthcare supplier and also you’d like to search out out for those who may qualify to be one among a restricted variety of clinics offering X cell know-how, please contact Dr. Lieurance and his crew through electronic mail at [email protected] or go to www.xcell.us. 

To find extra about all the modern rejuvenating practices and longevity-enhancing strategies Dr. Lieurance practices, you may also take a look at our podcasts collectively:

• Loopy Prostate Injections, Cranium-Cracking Nasal Changes, Defying Illness, Revitalizing Cells, And Safeguarding Your Sexuality With Dr. John Lieurance
• “The Loopy Future Of Medical Biohacking: Cranium Resets, Suppositories, Nasal Sprays, Nebulizers, Sound Remedy & Extra With Dr. John Lieurance. [Best of BGF]”
• “The ‘Dr. Unusual’ Of Medication & Biohacking: Methylene Blue, Stem Cells, Lasers, Earth, Air, Water, Fireplace & Extra With Dr. John Lieurance.”
• “The Stunning Fact About Excessive-Dose Melatonin, Does Melatonin Supplementation Shut Down Your Personal Manufacturing, How To Use Melatonin To Improve Fasting & A lot Extra With Dr. John Lieurance.”

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• Ibid.
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